Leydig cell dysfunction is associated with post-transcriptional deregulation of CYP17A1 in men with Sertoli cell-only syndrome
نویسندگان
چکیده
منابع مشابه
Predictive Factors of Successful Microdissection Testicular Sperm Extraction in Patients with Presumed Sertoli Cell-Only Syndrome
Background To evaluate predictive factors of successful microdissection-testicular sperm extraction (MD-TESE) in patients with presumed Sertoli cell-only syndrome (SCOS). MaterialsAndMethods In this retrospective analysis, 874 men with non-obstructive azoospermia (NOA), among whom 148 individuals with diagnosis of SCOS in prior biopsy, underwent MD-TESE at Department of Andrology, Royan Institu...
متن کاملSertoli cell-only syndrome
Sertoli cell-only syndrome is defined by the complete absence of germ cells in testicular tissues and always results in male infertility. Germ cells give rise to next stages of spermatogenesis which is the process of sperm formation. They are normally attached to Sertoli cells forming together so called seminiferous tubules which form testicular tissue. If there are only Sertoli cells, then n...
متن کاملSertoli cell-only syndrome
Sertoli cell-only syndrome is defined by the complete absence of germ cells in testicular tissues and always results in male infertility. Germ cells give rise to next stages of spermatogenesis which is the process of sperm formation. They are normally attached to Sertoli cells forming together so called seminiferous tubules which form testicular tissue. If there are only Sertoli cells, then n...
متن کاملSertoli cell only syndrome.
Sertoli cell only syndrome was first described by Del Castillo et al. (1947). According to the original description it has been used when no spermatogenic cells have been seen in a testicular biopsy specimen. It is therefore unfortunate that the name of this syndrome has been misused in Human Reproduction in connection with cases where Sertoli cell only has been a diagnostic failure by a pathol...
متن کاملSertoli cell-only syndrome
Sertoli cell-only syndrome is defined by the complete absence of germ cells in testicular tissues and always results in male infertility. Germ cells give rise to next stages of spermatogenesis which is the process of sperm formation. They are normally attached to Sertoli cells forming together so called seminiferous tubules which form testicular tissue. If there are only Sertoli cells, then n...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: MHR: Basic science of reproductive medicine
سال: 2018
ISSN: 1460-2407
DOI: 10.1093/molehr/gay006